Recombinant human CDC37 protein
CDC37, an essential gene in Saccharomyces cerevisiae, interacts genetically with multiple protein kinases. Cdc37 associates with the heat-shock protein 90 (Hsp90) molecular chaperone as one of several auxiliary proteins that are collectively referred to as Hsp90 co-chaperones. Cdc37 up-regulation is a common early event in some localized human cancers. Recombinant CDC37 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
44.4Da (378aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Boudeau J., (2003) Biochem J. 370 (3) :849-57; ; Abbas-Terki T., (2002) Biol Chem. 383 (9) :1335-42;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_008996
Uniprot Accession Number
Q16543
Species
Human
AA Sequence
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