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Recombinant human CEBP gamma/CEBPG protein

CCAAT/enhancer binding protein (C/EBP) gamma is a family of transcription factors all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta gamma, delta, that form homodimers and/or form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBP gamma may cooperate with Fos to bind PRE- enhancer elements. The DNA binding domain of CEBP-gamma (amino acid residues, 39-147) was produced in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CCAAT/enhancer-binding protein gamma, C/EBP gamma, GPE1BP, IG/EBP-1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

16.5 kDa (146aa) confirmed by MALDI-TOF

Additionnal Information

CEBP-g, CCAAT/enhancer binding protein g, CEBPG, CEBP-gamma, His-tag (DNA binding domain, residues), C/EBP gamma, CCAAT/enhancer-binding protein gamma, CCAAT/enhancer binding protein g C/EBP gamma, CCAAT/enhancer binding protein (C/EBP) gamma, CCAAT/enhancer binding protein gamma, GPE1BP, IG/EBP 1, IG/EBP1, CBP3003-10 µg, CBP3003-20 µg, CBP3003-50 µg, CBP3003-100 µg, CBP3003-250 µg, CBP3003-500 µg, CBP3003-1 mg, CBP3003-10, CBP3003-20, CBP3003-50, CBP3003-100, CBP3003-250, CBP3003-500, CBP3003-1

References & Citations

Hattori, T., et al (2003) Oncogene 22 (9) . ,1273-1280; ; Davydov, I., et al (1995) Gene. 161 (2) ; ; 271-275; ; Williams, S.C., et al (1991) Genes Dev. 5 (9) ; ; 1553-1567;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl, 5mM beta-Mercaptoethanol

Scientific Category

Cell Cycle

NCBI Accession Number

NP_001797.1

Uniprot Accession Number

P53567

Species

Human

AA Sequence

PGG GGKAVAPSKQ SKKSSPMDRN SDEYRQRRER NNMAVKKSRL KSKQKAQDTL QRVNQLKEEN ERLEAKIKLL TKELSVLKDL FLEHAHNLAD NVQSISTENT TADGDN

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