Recombinant human Biliverdin Reductase B/BLVRB protein
Biliverdin reductase B (BLVRB) is an enzyme (EC 1. 3. 1. 24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
22.1 kDa (206aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
L. Lee Grismer., et al. (2007) . Herpetologica. 63 (3) :392-400; ; Baranano DE., et al. (2002) . Proc Natl Acad Sci uSA. 99 (25) :16093-8;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.5) containing 10% glycerol, 1mM DTT
Scientific Category
Redox Proteins
NCBI Accession Number
NP_000704.1
Uniprot Accession Number
P30043
Species
Human
AA Sequence
Frequently Asked Questions
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