Recombinant human Biliverdin Reductase B/BLVRB protein

Biliverdin reductase B (BLVRB) is an enzyme (EC 1. 3. 1. 24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

BLVRB, FLR, BVRB, SDR43u1, MGC117413, Biliverdin reductase B, Biliverdin IX beta reductase, BVR B, Flavin reductase, Flavin reductase (NADPH), FR, GHBP, Green heme binding protein, MGC117413, NADPH dependent diaphorase, NADPH flavin reductase.

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

22.1 kDa (206aa) confirmed by MALDI-TOF

Additionnal Information

Biliverdin Reductase B, BLVRB, BLVRB, FLR, BVRB, SDR43u1, MGC117413, Biliverdin reductase B, Biliverdin IX beta reductase, BVR B, Flavin reductase, Flavin reductase (NADPH), FR, GHBP, Green heme binding protein, MGC117413, NADPH dependent diaphorase, NADPH flavin reductase., BVR0901-10 µg, BVR0901-20 µg, BVR0901-50 µg, BVR0901-100 µg, BVR0901-250 µg, BVR0901-500 µg, BVR0901-1 mg, BVR0901-10, BVR0901-20, BVR0901-50, BVR0901-100, BVR0901-250, BVR0901-500, BVR0901-1

References & Citations

L. Lee Grismer., et al. (2007) . Herpetologica. 63 (3) :392-400; ; Baranano DE., et al. (2002) . Proc Natl Acad Sci uSA. 99 (25) :16093-8;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.5) containing 10% glycerol, 1mM DTT

Scientific Category

Redox Proteins

NCBI Accession Number

NP_000704.1

Uniprot Accession Number

P30043

Species

Human

AA Sequence

MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ