Recombinant human BNP protein

BNP (Brain natriuretic peptide) is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. BNP is a 32 amino acid polypeptide and is co-secreted along with a 76 amino acid N-terminal fragment which is biologically inactive. This protein has biological actions including natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Recombinant human BNP, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Brain natriuretic peptide (type B natriuretic peptide), NPPB, GC-B, Brain natriuretic peptide (type B natriuretic peptide), BNP, Brain natriuretic peptide (type B natriuretic peptide) Gamma brain natriuretic peptide, Natriuretic peptide precursor B, Natriuretic peptides B

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 85% by SDS-PAGE

Molecular Weight

14 kDa (129aa) confirmed by MALDI-TOF

Additionnal Information

BNP, Brain natriuretic peptide (type B natriuretic peptide), NPPB, GC-B, Brain natriuretic peptide (type B natriuretic peptide), BNP, Brain natriuretic peptide (type B natriuretic peptide) Gamma brain natriuretic peptide, Natriuretic peptide precursor B, Natriuretic peptides B, BNP0801-10 µg, BNP0801-20 µg, BNP0801-50 µg, BNP0801-100 µg, BNP0801-250 µg, BNP0801-500 µg, BNP0801-1 mg, BNP0801-10, BNP0801-20, BNP0801-50, BNP0801-100, BNP0801-250, BNP0801-500, BNP0801-1