Recombinant human BMP-7 (monomer) protein

Bone morphogenic protein-7 (BMP-7/OP-1) is a member of the transforming growth factor-beta (TGF-beta) superfamily. Like other members of the BMPs family, it plays a role in calcium regulation and bone homeostasis. BMPs have been also shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. BMP7 also has the potential for treatment of chronic kidney disease. Recombinant human BMP-7 protein was expressed in E. coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.

Product Specifications

Product Name Alternative

BMP 7, Bone morphogenetic protein 7, Eptotermin alfa, OP-1, Osteogenic protein 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

16.8 kDa (148aa) confirmed by MALDI-TOF

Additionnal Information

BMP7 (monomer), BMP-7, BMP0906-10 µg, BMP0906-20 µg, BMP0906-50 µg, BMP0906-100 µg, BMP0906-250 µg, BMP0906-500 µg, BMP0906-1 mg, BMP0906-10, BMP0906-20, BMP0906-50, BMP0906-100, BMP0906-250, BMP0906-500, BMP0906-1