What is the catalog number for Recombinant human GFR alpha-1 protein?

The catalog number for Recombinant human GFR alpha-1 protein is ATGP4154-020.

What sizes are available for Recombinant human GFR alpha-1 protein?

Recombinant human GFR alpha-1 protein is available in the following size(s): 20 µg.

Is Recombinant human GFR alpha-1 protein in stock?

Recombinant human GFR alpha-1 protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human GFR alpha-1 protein

GFR alpha-1, also known as GDNF family receptor alpha-1, belongs to the GDNFR family. It is a glycosylphosphatidylinositol (GPI) -linked receptor found on the cell surface, acting as a receptor for both GDNF and NTN and function as neurotrophic factors for a variety of neuronal populations in the central and peripheral nervous systems. It bind GDNF strongly and activate RET tyrosine kinase and is also essential for the development of kidneys and the enteric nervous system. Recombinant human GFR alpha-1, fused to hIgG-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Human GDNF (CAT# ATGP3942) is coated at 0.5 µg/mL (100 ul/well) can bind Human GFR alpha-1. The ED50 range ≤ 50 ng/mL.

Product Name Alternative

GDNF family receptor alpha-1 isoform b, GDNF receptor alpha-1, GDNF R alpha-1, GFR alpha1, GFR-ALPHA-1, GFRa-1, GFRalpha-1, GFRA1, GDNFR, GDNFRA, RET1L, RETL1, TRNR1, RHDA4, RET ligand, TGF-beta-related neurotrophic factor receptor 1

Expression System

HEK293

Antigen Species

Human

Tag

HIgG-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA with Human GDNF (CAT# ATGP3942) . The ED50 range ≤ 50 ng/mL.

Molecular Weight

70.8 kDa (633aa)

Additionnal Information

ATGP4154-10 µg, ATGP4154-20 µg, ATGP4154-50 µg, ATGP4154-100 µg, ATGP4154-250 µg, ATGP4154-500 µg, ATGP4154-1 mg, ATGP4154-010, ATGP4154-020, ATGP4154-050, ATGP4154-100, ATGP4154-250, ATGP4154-500, ATGP4154-01M

References & Citations

Thompson, J. et al. (1998) Mol. Cell Neurosci. 11:117-126.; ; Baloh, R.H. et al. (1998) Proc. Natl. Acad. Sci. USA 95:5801-5806.; ; Jing S, et al. (1996) . Cell. 85:1113-1124.; ; Treanor JJ, et al. (1996) . 382: 80-83.; ; Jing S, et al. (1997) . J Biol Chem. 272: 33111-33117.;