Recombinant human HLF protein
HLF, also known as hepatic leukemia factor, belongs to the bZIP family and the PAR (proline and acidic-rich) subfamily of transcription regulatory proteins. HLF binds DNA specifically as a homodimer or heterodimer with other PAR factors. It is highly expressed in liver, with lower levels in lung and kidney and functions as a potent trans-activator. Recombinant human HLF protein, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Hepatic leukemia factor, PAR bZIP transcription factor, E2A-HLF fusion transcript protein
Expression System
HEK293
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
34kDa (301aa)
Additionnal Information
References & Citations
Hunger S.P. et al. (1992) Genes Dev. 6: 1608-1620.; ; Falvey E. et al. (1995) EMBO J. 14: 4307-4317.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_002117.1
Uniprot Accession Number
Q16534
Species
Human
N Terminal Sequence
Met1
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