Recombinant mouse CD99-L2 protein
CD99-L2, also known as CD99 antigen-like protein 2, belongs to theCD99 family. It is endothelial surface protein involved in neutrophil extravasation and was expressed at the borders between transfected cells. It display a role in the migration of leukocytes across endothelial cells of inflammation, and play other roles in thymocyte development. It could trigger homotypic cell aggregation by stimulating other adhesion molecules or effects on the membrane underlying cytoskeleton. Recombinant mouse CD99-L2, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
CD99 antigen-like protein 2 isoform 1, Cd99l2, Mic2l1, Xap89, Mic2l1, CD99 antigen-like protein 2, MIC2-like protein 1
Expression System
HEK293
Antigen Species
Mouse
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
41.8kDa (378aa)
Additionnal Information
References & Citations
ALAN R., et al, (2007) Cell Commun. Adhes. 14:227-237.; ; Bixel G., et al, (2007) Blood 109:5327-5336.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001186278.1
Uniprot Accession Number
Q8BIF0
Species
Mouse
N Terminal Sequence
Asp
AA Sequence
DTDGFNL EDALKETSSV KQRWDHFSTT TRRPVTTRAP ANPAERWDHV ATTTTRRPGT TRAPSNPMEL DGFDLEDALD DRNDLDGPKK PSAGEAGGWS DKDLEDIVEG GGYKPDKNKG GGGYGSNDDP GSGISTETG
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