Recombinant mouse CD31/PECAM1 protein

CD31, also known as PECAM-1 (platelet endothelial cell adhesion molecule), is a member of the immunoglobulin superfamily. It is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It plays a role in signalling and is involved in migration of monocytes and neutrophils, natural killer cells, T lymphocytes and CD34+ hematopoietic progenitor cells. Also, it is important for angiogenesis because it enables the formation of new blood vessels through the cell-cell adhesion. It may play a role in a variety of diseases, including cancer, atherosclerosis, and the nervous system diseases. Recombinant mouse CD31/PECAM-1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CD31/EndoCAM, CD31, EndoCAM, GPIIA', PECA1, PECAM1, PECAM-1, Platelet endothelial cell adhesion molecule 1

Expression System

HEK293

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

65.3kDa (579aa)

Additionnal Information

ATGP4092-10 µg, ATGP4092-20 µg, ATGP4092-50 µg, ATGP4092-100 µg, ATGP4092-250 µg, ATGP4092-500 µg, ATGP4092-1 mg, ATGP4092-10, ATGP4092-20, ATGP4092-50, ATGP4092-100, ATGP4092-250, ATGP4092-500, ATGP4092-1

References & Citations

DeLisser HM., et al, (1997) Am J Pathol. 151:671-677.; ; Albelda SM., et al, (1991) J Cell Biol. 114:1059–1068.; ; Elias CG., et al, (1998) European Journal of Immunology. 28:1948–1958.