Recombinant mouse CD31/PECAM1 protein
CD31, also known as PECAM-1 (platelet endothelial cell adhesion molecule), is a member of the immunoglobulin superfamily. It is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It plays a role in signalling and is involved in migration of monocytes and neutrophils, natural killer cells, T lymphocytes and CD34+ hematopoietic progenitor cells. Also, it is important for angiogenesis because it enables the formation of new blood vessels through the cell-cell adhesion. It may play a role in a variety of diseases, including cancer, atherosclerosis, and the nervous system diseases. Recombinant mouse CD31/PECAM-1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
CD31/EndoCAM, CD31, EndoCAM, GPIIA', PECA1, PECAM1, PECAM-1, Platelet endothelial cell adhesion molecule 1
Expression System
HEK293
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
65.3kDa (579aa)
Additionnal Information
References & Citations
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_032842.2
Uniprot Accession Number
Q08481
Species
Mouse
N Terminal Sequence
Glu 18
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