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Recombinant human Alpha 1-Acid Glycoprotein 1/ORM1 protein

Alpha 1-Acid Glycoprotein 1 also known as ORM1, is a member of the inositol calycin superfamily. It is an acute phase plasma protein synthesized by the liver. The specific function of this protein has not yet been determined. However, it may be involved in aspects of immunosuppression. The protein is believed to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, also regulates the extravasation of the cells during infection and inflammation. Expression of ORM1 is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. Recombinant human Alpha 1-Acid Glycoprotein 1/ORM1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Orosomucoid-1, ORM, AGP1, AGP-A, HEL-S-153w

Expression System

HEK293

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

22.4kDa (189aa)

Additionnal Information

ATGP4089-10 µg, ATGP4089-20 µg, ATGP4089-50 µg, ATGP4089-100 µg, ATGP4089-250 µg, ATGP4089-500 µg, ATGP4089-1 mg, ATGP4089-10, ATGP4089-20, ATGP4089-50, ATGP4089-100, ATGP4089-250, ATGP4089-500, ATGP4089-1, ATGP1143-10 µg, ATGP1143-20 µg, ATGP1143-50 µg, ATGP1143-100 µg, ATGP1143-250 µg, ATGP1143-500 µg, ATGP1143-1 mg, ATGP1143-10, ATGP1143-20, ATGP1143-50, ATGP1143-100, ATGP1143-250, ATGP1143-500, ATGP1143-1

References & Citations

Umetsu K., et al. (1986) Hum Genet. 71:223-224.; ; Carter K C., et al. (1991) Biochim. Biophys. Acta. 1089:197-205.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_000598.2

Uniprot Accession Number

P02763

Species

Human

N Terminal Sequence

Gln 19

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