Recombinant human Angiopoietin-like 7/ANGPTL7 protein

Angiopoietin-like 7, also known as Angiopoietin-related protein 7, is a member of angiopoietin-like (ANGPTL) family. Angiopoietin-like 7 have been shown to be involved in blood vessel formation or neovascularization in several models. When overexpressed in tumor cells it promotes collagen and proteoglycan deposition but inhibits tumor xenograft progression and tumor angiogenesis. It is also expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Overexpression of ANGPTL7 increases collagen expression. Thus, it could have a pathogenic role in glaucoma, and may serve as a potential therapeutic target. Recombinant human Angiopoietin-like 7, fused to hIgG-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Angiopoietin like 7, AngX, CDT6, Angiopoietin-related protein 7, ANGPTL7

Expression System

HEK293

Antigen Species

Human

Tag

HIgG-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS - PAGE

Molecular Weight

63.2kDa (553aa)

Additionnal Information

Angiopoietin like7, angiopoietin like 7, Angiopoietin like factor, Angiopoietin-like factor; Angiopoietin-like Protein 7, angiopoietin-related protein 7, ANGPTL7, AngX, CDT6, Cornea-derived transcript 6 protein, dJ647M16.1, ATGP4082-10 µg, ATGP4082-20 µg, ATGP4082-50 µg, ATGP4082-100 µg, ATGP4082-250 µg, ATGP4082-500 µg, ATGP4082-1 mg, ATGP4082-010, ATGP4082-020, ATGP4082-050, ATGP4082-100, ATGP4082-250, ATGP4082-500, ATGP4082-01M