Recombinant human PKC iota protein

PKC iota, also known as Protein Kinase C iota, is a member of serine/threonine protein kinases family. It play a key regulatory role in a number of cellular functions including cell growth and differentiation, hormone secretion, and gene expression. It is involved in cell polarization processes and the formation of epithelial tight junctions. This protein kinase is calcium-independent and phospholipid-dependent. It is also implicated in the activation of several signaling pathways including Ras, c-Src and NF-kappa-B pathways. Recombinant human PKC iota, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

DXS1179E, nPKC-iota, PKCI, aPKC-lambda/iota, PRKC-lambda/iota, Protein kinase C iota type, Atypical protein kinase C-lambda/iota, PRKCL, Protein Kinase C iota, PRKCI

Expression System

HEK293

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 80% by SDS - PAGE

Molecular Weight

69kDa (602aa)

Additionnal Information

ATGP4081-10 µg, ATGP4081-20 µg, ATGP4081-50 µg, ATGP4081-100 µg, ATGP4081-250 µg, ATGP4081-500 µg, ATGP4081-1 mg, ATGP4081-10, ATGP4081-20, ATGP4081-50, ATGP4081-100, ATGP4081-250, ATGP4081-500, ATGP4081-1