Recombinant human Serpin B2/PAI-2 protein

SERPINB2 belongs to the serpin family. This protein inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. Recombinant human SERPINB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Plasminogen activator inhibitor 2, HsT1201, PAI, PAI-2, PAI2, PLANH2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

49.0 kDa (438aa) confirmed by MALDI-TOF

Additionnal Information

Serpin B2, PAI2, Plasminogen activator inhibitor 2, HsT1201, PAI, PAI-2, PAI2, PLANH2, ATGP2847-10 µg, ATGP2847-20 µg, ATGP2847-50 µg, ATGP2847-100 µg, ATGP2847-250 µg, ATGP2847-500 µg, ATGP2847-1 mg, ATGP2847-10, ATGP2847-20, ATGP2847-50, ATGP2847-100, ATGP2847-250, ATGP2847-500, ATGP2847-1

References & Citations

Schleuning W.-D., et al, (1987) Mol. Cell. Biol. 7:4564-4567.; ; Ye R.D., et al, (1989) J. Biol. Chem. 264:5495-5502.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_001137290

Uniprot Accession Number

P05120

Species

Human

AA Sequence

MEDLCVA NTLFALNLFK HLAKASPTQN LFLSPWSISS TMAMVYMGSR GSTEDQMAKV LQFNEVGANA VTPMTPENFT SCGFMQQIQK GSYPDAILQA QAADKIHSSF RSLSSAINAS TGNYLLESVN KLFGEKSASF REEYIRLCQK YYSSEPQAVD FLECAEEARK KINSWVKTQT KGKIPNLLPE GSVDGDTRMV LVNAVYFKGK WKTPFEKKLN GLYPFRVNSA QRTPVQMMYL REKLNIGYIE DLKAQILELP YAGDVSMFLL LPDEIADVST GLELLESEIT YDKLNKWTSK DKMAEDEVEV YIPQFKLEEH YELRSILRSM GMEDAFNKGR ANFSGMSERN DLFLSEVFHQ AMVDVNEEGT EAAAGTGGVM TGRTGHGGPQ FVADHPFLFL IMHKITNCIL FFGRFSSP