Recombinant human CD9 protein

CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant human CD9, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

CD9 antigen, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29, BA2,5H9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, p24, CD9 antigen isoform1

Expression System

HEK293

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS - PAGE

Molecular Weight

10.7kDa (93aa)

Additionnal Information

ATGP4064-10 µg, ATGP4064-20 µg, ATGP4064-50 µg, ATGP4064-100 µg, ATGP4064-250 µg, ATGP4064-500 µg, ATGP4064-1 mg, ATGP4064-10, ATGP4064-20, ATGP4064-50, ATGP4064-100, ATGP4064-250, ATGP4064-500, ATGP4064-1

References & Citations

Sara J, Eileen M, et al. (2001) . Thromb Haemost. 85 (1) :134-141.; ; Rubinstein E, Billard M, et al. (1993) . Thrombosis Research. 71 (5) : 377–383.; ; Blake DJ, Martiszus JD, et al. (2018) . Cytokine. 111: 567–570.