Recombinant human Renin protein

Renin, also known as REN, is a member of the peptidase A1 family. It is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. It is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Recombinant human Renin, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

REN, renin, ADTKD4, HNFJ2, RTD, Angiotensinogenase

Expression System

HEK293

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

43.1 kDa (389aa)

Additionnal Information

ATGP4050-10 µg, ATGP4050-20 µg, ATGP4050-50 µg, ATGP4050-100 µg, ATGP4050-250 µg, ATGP4050-500 µg, ATGP4050-1 mg, ATGP4050-10, ATGP4050-20, ATGP4050-50, ATGP4050-100, ATGP4050-250, ATGP4050-500, ATGP4050-1