Recombinant rat ACE-2 protein

ACE-2, also known as angiotensin-converting enzyme 2, is carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. It is able to hydrolyze apelin-13 and dynorphin-13 with high efficiency and may be an important regulator of heart function. Recombinant rat ACE-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Specific activity is > 150 pmol/min/ug, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Mca-YVADAPK (Dnp) -OH per minute at pH 7.5, at 25C.

Product Name Alternative

ACE2, angiotensin-converting enzyme2, Ace2, ACE-related carboxypeptidase

Expression System

Baculovirus

Antigen Species

Rat

Tag

His-Tag

Applications

SDS-PAGE, Enzyme Activity

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Bioactivity

Specific activity is > 150 pmol/min/ug, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Mca-YVADAPK (Dnp) -OH per minute at pH 7.5, at 25C.

Molecular Weight

84.7 kDa (731aa)

Additionnal Information

ATGP4048-10 µg, ATGP4048-20 µg, ATGP4048-50 µg, ATGP4048-100 µg, ATGP4048-250 µg, ATGP4048-500 µg, ATGP4048-1 mg, ATGP4048-10, ATGP4048-20, ATGP4048-50, ATGP4048-100, ATGP4048-250, ATGP4048-500, ATGP4048-1