Recombinant human Selenoprotein W/SELENOW protein

SEPW1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the uGA codon that normally signals translation termination. The 3 uTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of uGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34. Recombinant human SEPW1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Selenoprotein W, selW, SEPW1, Selenoprotein W1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by BRADFORD assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

11.8 kDa (110aa) confirmed by MALDI-TOF

Additionnal Information

SEPW1, Selenoprotein W, selW, ATGP2813, ATGP4033-10 µg, ATGP4033-20 µg, ATGP4033-50 µg, ATGP4033-100 µg, ATGP4033-250 µg, ATGP4033-500 µg, ATGP4033-1 mg, ATGP4033-10, ATGP4033-20, ATGP4033-50, ATGP4033-100, ATGP4033-250, ATGP4033-500, ATGP4033-1