What is the catalog number for Recombinant human Cathepsin F protein?

The catalog number for Recombinant human Cathepsin F protein is ATGP4026-010.

What sizes are available for Recombinant human Cathepsin F protein?

Recombinant human Cathepsin F protein is available in the following size(s): 10 µg.

Is Recombinant human Cathepsin F protein in stock?

Recombinant human Cathepsin F protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human Cathepsin F protein

Cathepsin F, also known as CTSF, belongs to the cathepsin family. Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. This protein is thought to play a role in normal protein catabolism, and because it is highly expressed in some cancer cell lines, it may be involved in degradative processes occurring during tumor progression. The CTSF gene may function as a tumor suppressor in Gastric cancer and may be a potential therapeutic target in the treatment of Gastric cancer. It also can be used as an alternative way to test for the disease known as Opisthorchis Viverrini. Recombinant human Cathepsin F protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Specific activity is > 5 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1pmole of Z-Phe-Arg-AMC to Z-Phe-Arg and AMC per minute at pH 5.0 at 37°C.

Product Name Alternative

CTSF, CATSF, CLN13

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Enzyme Activity

Concentration

0.25 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Specific activity is > 5 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1pmole of Z-Phe-Arg-AMC to Z-Phe-Arg and AMC per minute at pH 5.0 at 37°C.

Molecular Weight

52.5kDa (474aa)

Additionnal Information

ATGP4026-10 µg, ATGP4026-20 µg, ATGP4026-50 µg, ATGP4026-100 µg, ATGP4026-250 µg, ATGP4026-500 µg, ATGP4026-1 mg, ATGP4026-10, ATGP4026-20, ATGP4026-50, ATGP4026-100, ATGP4026-250, ATGP4026-500, ATGP4026-1, ATGP4026-10 µg, ATGP4026-20 µg, ATGP4026-50 µg, ATGP4026-100 µg, ATGP4026-250 µg, ATGP4026-500 µg, ATGP4026-1 mg, ATGP4026-10, ATGP4026-20, ATGP4026-50, ATGP4026-100, ATGP4026-250, ATGP4026-500, ATGP4026-1

References & Citations

Schmitz J., et al, (2015) ChemMedChem. 10:1365-1377.; ; Ji C., et al, (2018) Oncol Res. 26:83-93.; ; Kulkarni G., et al, (2021) Schizophr Res. 228:435-437.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 40% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_003784

Uniprot Accession Number

Q9UBX1

Species

Human

N Terminal Sequence

Ala

AA Sequence

APAQPRA ASFQAWGPPS PELLAPTRFA LEMFNRGRAA GTRAVLGLVR GRVRRAGQGS LYSLEATLEE PPCNDPMVCR LPVSKKTLLC SFQVLDELGR HVLLRKDCGP VDTKVPGAGE PKSAFTQGSA MISSLSQNHP DNRNETFSSV ISLLNEDPLS QDLPVKMASI FKNFVITYNR TYESKEEARW RLSVFVNNMV RAQKIQALDR GTAQYGVTKF SDLTEEEFRT IYLNTLLRKE PGNKMKQAKS VGDLAPPEWD WRSKGAVTKV KDQGMCGSCW AFSVTGNVEG QWFLNQGTLL SLSEQELLDC DKMDKACMGG LPSNAYSAIK NLGGLETEDD YSYQGHMQSC NFSAEKAKVY INDSVELSQN EQKLAAWLAK RGPISVAINA FGMQFYRHGI SRPLRPLCSP WLIDHAVLLV GYGNRSDVPF WAIKNSWGTD WGEKGYYYLH RGSGACGVNT MASSAVVD