Recombinant human CD47 protein

CD47, also known as leukocyte surface antigen CD47 isoform 1, has a role in both cell adhesions by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Recombinant human CD47, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Human CD47 is coated at 1 µg/mL (100 ul/well) can bind Human SIRP gamma/CD172g (CAT# ATGP4030) in a Functional ELISA assay.

Product Name Alternative

CD47, OA3, IAP, MER6, Leukocyte surface antigen CD47 isoform 1, antigenic surface determinant protein OA3, Integrin-associated protein

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA with Human SIRP gamma/CD172g (CAT# ATGP4030)

Molecular Weight

14.7 kDa (129aa)

Additionnal Information

ATGP3188, ATGP4015-10 µg, ATGP4015-20 µg, ATGP4015-50 µg, ATGP4015-100 µg, ATGP4015-250 µg, ATGP4015-500 µg, ATGP4015-1 mg, ATGP4015-10, ATGP4015-20, ATGP4015-50, ATGP4015-100, ATGP4015-250, ATGP4015-500, ATGP4015-1, ATGP4015-10 µg, ATGP4015-20 µg, ATGP4015-50 µg, ATGP4015-100 µg, ATGP4015-250 µg, ATGP4015-500 µg, ATGP4015-1 mg, ATGP4015-10, ATGP4015-20, ATGP4015-50, ATGP4015-100, ATGP4015-250, ATGP4015-500, ATGP4015-1