Recombinant rat CCL2/MCP-1 protein

Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1) . CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It binds to chemokine receptors CCR2 and CCR4. It also induces enzyme and cytokine release by monocytes, NK cells and lymphocytes, and histamine release by basophils, primarily due to interaction with CCR2 receptors on these cells. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. Recombinant rat CCL2/JE/MCP-1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

C-C motif chemokine 2, HC11, JE, MCAF, MCP-1, MCP1, Scya2, Sigje, SMC-CF, Immediate-early serum-responsive protein JE, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, Small-inducible cytokine A2

Expression System

Baculovirus

Antigen Species

Rat

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

15.1kDa (134aa)

Additionnal Information

ATGP4002-10 µg, ATGP4002-50 µg, ATGP4002-100 µg, ATGP4002-200ug, ATGP4002-250 µg, ATGP4002-500 µg, ATGP4002-1 mg, ATGP4002-10 µg, ATGP4002-20 µg, ATGP4002-50 µg, ATGP4002-100 µg, ATGP4002-250 µg, ATGP4002-500 µg, ATGP4002-1 mg, ATGP4002-10, ATGP4002-20, ATGP4002-50, ATGP4002-100, ATGP4002-250, ATGP4002-500, ATGP4002-1