Recombinant human LBP protein

LBP, also known as Lipopolysaccharide-binding protein, is a glycoprotein member of the BPI/LBP family of lipid-binding proteins. LBP is a glycoprotein that is synthesized principally by hepatocytes. It binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. It binds to LPS to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4. Recombinant human LBP, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Lipopolysaccharide-binding protein, LBP, BPIFD2, MGC22233, LCD-binding protein, OTTHUMP00000030965

Expression System

HEK293

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

51.7kDa (462aa)

Additionnal Information

, ATGP3989-10 µg, ATGP3989-20 µg, ATGP3989-50 µg, ATGP3989-100 µg, ATGP3989-250 µg, ATGP3989-500 µg, ATGP3989-1 mg, ATGP3989-10, ATGP3989-20, ATGP3989-50, ATGP3989-100, ATGP3989-250, ATGP3989-500, ATGP3989-1

References & Citations

J. Weiss, 2003, Biochemical Society Transactions: Volume 31, part 4: 785-790.; ; Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430.;