Recombinant human ICAM-5 protein

ICAM-5, also known as telencephalin, is a cell surface glycoprotein belonging to the immunoglobulin superfamily. Human ICAM-5 is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. The tissue of ICAM-5, being expressed only in telencephalic regions of the central nervous system. Like other ICAMs, ICAM-5 binds to the leukocyte integrin LFA-1. Recombinant human ICAM-5, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Intercellular adhesion molecule 5, ICAM5, ICAM-5, Telencephalin, telencephalin, TLN, TLCN, TLNtelencephalin, TLCNTelencephalin

Expression System

HEK293

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

113.8kDa (1052aa)

Additionnal Information

, ATGP3957-10 µg, ATGP3957-20 µg, ATGP3957-50 µg, ATGP3957-100 µg, ATGP3957-250 µg, ATGP3957-500 µg, ATGP3957-1 mg, ATGP3957-10, ATGP3957-20, ATGP3957-50, ATGP3957-100, ATGP3957-250, ATGP3957-500, ATGP3957-1

References & Citations

Yoshihara, Y. et al. (1994) Neuron 12:541-553.; ; Tain, L. et al. (2000) Eur. J. Immunol. 30:810-818.; ; Mizuno, T. et al. (1997) J. Biol. Chem. 272:1156-1163.