Recombinant human Kallikrein 3/PSA protein
Kallikrein 3, as known as prostate specific antigen (PSA), is a subgroup of serine proteases, enzymes capable of cleaving peptide bonds in proteins. This protein is expressed in the prostate and is thought to be responsible for regulating semen liquefaction through hydrolysis of seminogelin. It is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. Recombinant human Kallikrein 3 protein, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.
Product Specifications
Specifications
Product Name Alternative
Expression System
HEK293
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Enzyme Activity
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Bioactivity
Molecular Weight
27.6 kDa (250aa)
Additionnal Information
References & Citations
Hochmeister MN. et al. (1999) J Forensic Sci. J. 44:1057-1060. ; ; Jain, S. et al. (2002) Postgrad. Med. J. 78:646-650.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_001639.1
Uniprot Accession Number
P07288
Species
Human
N Terminal Sequence
Ala
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