Recombinant mouse MMP-2 protein

MMP-2, also known as Matrix metalloproteinase-2, is one of the f the matrix metalloproteinase (MMP) family.It is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonicdevelopment, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis andmetastasis. It has a role in myocardial cell death pathways and contributes to myocardial oxidative stress byregulating the activity of GSK3beta. This protein cleaves GSK3beta in vitro and involved in the formation of the fibrovascular tissues. Recombinant mouse MMP-2, fused to His-tag at C-terminus, was expressed ininsect cell and purified by using conventional chromatography techniques.