Recombinant mouse FGF-21 protein
FGF-21, also known as fibroblast growth factor 21, is a member of the fibroblast growth factor family. It has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. It stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. Recombinant mouse FGF-21, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
FGF 21, FGF-21, Fgf21, FGF21_HUMAN, FGFL, Fibroblast growth factor 21, PRO10196, UNQ3115
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
22.5 kDa (206aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Kharitonenkov A., et al. (2005) J Clin Invest. 115:1627-1635.; ; Yamauchi H., et al. (2006) EMBO Rep. 7:649-654.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Growth factors
NCBI Accession Number
NP_064397
Uniprot Accession Number
Q9JJN1
Species
Mouse
AA Sequence
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