Recombinant mouse B7-H3 protein

B7H3, also known as CD276 antigen, is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. This protein plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. It induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. Recombinant mouse B7H3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CD276 antigen, Cd276, 6030411F23Rik, AU016588, B7h3, B7RP-2, B7 homolog 3, B7-H3

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.7 kDa (226aa)

Additionnal Information

B7-H3, ATGP3890-10 µg, ATGP3890-20 µg, ATGP3890-50 µg, ATGP3890-100 µg, ATGP3890-250 µg, ATGP3890-500 µg, ATGP3890-1 mg, ATGP3890-10, ATGP3890-20, ATGP3890-50, ATGP3890-100, ATGP3890-250, ATGP3890-500, ATGP3890-1, ATGP3890-10 µg, ATGP3890-20 µg, ATGP3890-50 µg, ATGP3890-100 µg, ATGP3890-250 µg, ATGP3890-500 µg, ATGP3890-1 mg, ATGP3890-10, ATGP3890-20, ATGP3890-50, ATGP3890-100, ATGP3890-250, ATGP3890-500, ATGP3890-1