Recombinant rat IL-2 protein

IL-2, also known as T cell growth factor (TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. Il-2/ Il-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant rat IL-2 was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Rat IL-2 stimulates cell proliferation of the CTLL2 mouse cytotoxic T cells. The ED50 range is less or equal to 0.3 ng/mL.

Product Name Alternative

Interleukin-2, IL-2, T-cell growth factor, TCGF

Expression System

E.coli

Antigen Species

Rat

Tag

Non-Tagged

Applications

SDS-PAGE, Bioactivity

Concentration

0.25 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is less or equal to 0.3 ng/mL.

Molecular Weight

15.6 kDa (136aa) confirmed by MALDI-TOF

Additionnal Information

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