What is the catalog number for Recombinant human Carboxylesterase 1/CES1 protein?

The catalog number for Recombinant human Carboxylesterase 1/CES1 protein is ATGP3862-200.

What sizes are available for Recombinant human Carboxylesterase 1/CES1 protein?

Recombinant human Carboxylesterase 1/CES1 protein is available in the following size(s): 200 µg.

Recombinant human Carboxylesterase 1/CES1 protein

Q: Is Recombinant human Carboxylesterase 1/CES1 protein in stock?

Recombinant human Carboxylesterase 1/CES1 protein is currently made to order / not held in immediate stock. Contact us for lead time.

Carboxylesterase 1, also known as liver carboxylesterase 1 isoform a, is a member of a large family of carboxylesterases. It is also part of the alpha/beta fold hydrolase family. Carboxylesterases hydrolyze long-chain fatty acid esters and thioesters. The resulting carboxylates are then often conjugated by other enzymes to increase solubility and eventually excreted. Also, this enzyme may play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. This protein is known to react aromatic and aliphatic esters and can manage cellular cholesterol esterification levels. It is present in most tissues with higher levels in the liver and low levels in the gastrointestinal tract. Recombinant human Carboxylesterase 1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Specific activity is > 700 pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to pnitrophenol per minute at pH 7.5 at 37C.

Product Name Alternative

Liver carboxylesterase 1 isoform a, CES1, ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

Enzyme Activity, SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Specific activity is > 700pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to pnitrophenol per minute at pH 7.5 at 37C.

Molecular Weight

61.7 kDa (559aa)

Additionnal Information

Carboxylesterase1, CES1, Carboxylesterase 1/CES1Liver carboxylesterase 1 isoform a, CES1, ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH, ATGP3862-10 µg, ATGP3862-20 µg, ATGP3862-50 µg, ATGP3862-100 µg, ATGP3862-250 µg, ATGP3862-500 µg, ATGP3862-1 mg, ATGP3862-10, ATGP3862-20, ATGP3862-50, ATGP3862-100, ATGP3862-250, ATGP3862-500, ATGP3862-1

References & Citations

Satoh T., et al, (2006) Chem Biol Interact. 162:195-211.; ; Redinbo MR., et al. (2005) Drug Discovery Today 10:313.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 25mM Sodium Acetate (pH 4.0) containing 10% glycerol, 0.1M NaCl, 0.1mM PMSF

Scientific Category

Cardiovascular

NCBI Accession Number

NP_001020366

Uniprot Accession Number

P23141

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADLGHPSSPP VVDTVHGKVL GKFVSLEGFA QPVAIFLGIP FAKPPLGPLR FTPPQPAEPW SFVKNATSYP PMCTQDPKAG QLLSELFTNR KENIPLKLSE DCLYLNIYTP ADLTKKNRLP VMVWIHGGGL MVGAASTYDG LALAAHENVV VVTIQYRLGI WGFFSTGDEH SRGNWGHLDQ VAALRWVQDN IASFGGNPGS VTIFGESAGG ESVSVLVLSP LAKNLFHRAI SESGVALTSV LVKKGDVKPL AEQIAITAGC KTTTSAVMVH CLRQKTEEEL LETTLKMKFL SLDLQGDPRE SQPLLGTVID GMLLLKTPEE LQAERNFHTV PYMVGINKQE FGWLIPMQLM SYPLSEGQLD QKTAMSLLWK SYPLVCIAKE LIPEATEKYL GGTDDTVKKK DLFLDLIADV MFGVPSVIVA RNHRDAGAPT YMYEFQYRPS FSSDMKPKTV IGDHGDELFS VFGAPFLKEG ASEEEIRLSK MVMKFWANFA RNGNPNGEGL PHWPEYNQKE GYLQIGANTQ AAQKLKDKEV AFWTNLFAKK AVEKPPQTEH IELHHHHHH