Recombinant mouse EGF-L6 protein

EGF-L6, also known as epidermal growth factor-like protein 6, is a member of the EGF repeat superfamily of proteins. This protein is expressed in fetal tissues during early development such as lung, heart, liver, spleen, cochlea, and placenta. This protein is expressed by epidermal stem cells in the hair follicle bulge and play a role in hair follicle morphogenesis through binding integrin alpha-8/beta-1. It is also produced by mature adipocytes and is thought to be involved in the process of adipose tissue expansion and the development of obesity. Recombinant mouse EGF-L6 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.