Recombinant human RELT/TNFRSF19L protein

RELT, also known tumor necrosis factor receptor superfamily member 19L, is one of the the tumor necrosis factor receptor superfamily. It is expressed in hematopoietic tissues and peripheral blood leukocytes. This protein mediates activation of NF-kappa-B and plays a role in T-cell activation. With overexpression of this protein in HEK-293 cells, it induces p38 and JNK signaling and activates apoptosis. And it can also costimulate T-cell proliferation in the presence of CD3 signaling. Recombinant human RELT protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 19L, RELT, TNFRSF19L, TRLT, RELT tumor necrosis factor receptor, Receptor expressed in Lymphoid tissues

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

41.4 kDa (376aa)

Additionnal Information

RELT, TNFRSF19L, RELT/TNFRSF19LTumor necrosis factor receptor superfamily member 19L, RELT, TNFRSF19L, TRLT, ATGP3847-10 µg, ATGP3847-20 µg, ATGP3847-50 µg, ATGP3847-100 µg, ATGP3847-250 µg, ATGP3847-500 µg, ATGP3847-1 mg, ATGP3847-10, ATGP3847-20, ATGP3847-50, ATGP3847-100, ATGP3847-250, ATGP3847-500, ATGP3847-1

References & Citations

Cusick JK., et al, (2010) Cell Immunol. 261:1-8.; ; Moua P., et al, (2017) Biochem Biophys Res Commun. 491:25-32.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_689408

Uniprot Accession Number

Q969Z4

Species

Human

N Terminal Sequence

Ser26

AA Sequence

STTLWQCPPG EEPDLDPGQG TLCRPCPPGT FSAAWGSSPC QPHARCSLWR RLEAQVGMAT RDTLCGDCWP GWFGPWGVPR VPCQPCSWAPLGTHGCDEWG RRARRGVEVA AGASSGGETR QPGNGTRAGG PEETAAQVEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH