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Recombinant rat IGF-1 protein

IGF-1, also known as Insulin-like growth factor I isoform d, is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF-1 is predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGF-1 belongs to the insulin gene family, which also contains insulin and relaxin. The IGF-1 is similar by structure and function to insulin, but has a much higher growth-promoting activity than insulin. Recombinant rat IGF-1 protein, was expressed in E. coli and purified by using conventional chromatography

Product Specifications

Product Name Alternative

Insulin-like growth factor I isoform d, IGF, IGF-I, Somatomedin

Expression System

E.coli

Antigen Species

Rat

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

7.8 kDa (71aa) confirmed by MALDI-TOF

Additionnal Information

IGF1, Insulin-like growth factor I isoform d, IGF, ATGP3840-10 µg, ATGP3840-20 µg, ATGP3840-50 µg, ATGP3840-100 µg, ATGP3840-250 µg, ATGP3840-500 µg, ATGP3840-1 mg, ATGP3840-10, ATGP3840-20, ATGP3840-50, ATGP3840-100, ATGP3840-250, ATGP3840-500, ATGP3840-1

References & Citations

Zumstein P., et al. (1987) J Biol Chem. 262 (33) : 11252-60.; ; Rabinovsky ED., et al. (2004) Neurol Res. 26 (2) : 204-10.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_001075948

Uniprot Accession Number

P08025

Species

Rat

AA Sequence

MGPETLCGAE LVDALQFVCG PRGFYFNKPT GYGSSIRRAP QTGIVDECCF RSCDLRRLEM YCAPLKPTKS A

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