Recombinant human IFN-alpha 7/IFNA7 protein
IFNA7, also known as interferon alpha-7, is a member of the interferon family. Interferon promotes the production of two enzymes, protein kinase and oligoadenylate synthetase. They allow the cells to communicate with the protective barrier of the immune system to eradicate pathogens or tumors. IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. IFN-alpha has both anti-viral and immunomodulatory activities on target cells, and increases the awareness of infection or tumor cells by elevating antigen presentation to T lymphocytes. This protein has both anti-viral and immunomodulatory activities on target cells and involved both in ligand binding and signal transduction. Recombinant human IFNA7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interferon alpha-7, IFNA7, IFN-alphaJ, IFNA-J, Interferon alpha-J1, IFN-alpha-J1
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
20.7 kDa (175aa)
Additionnal Information
References & Citations
De Veer MJ., et al. (2001) J Leukoc Biol. 69:912-920.; ; Fensterl V., et al. (2009) Biofactors. 35:14-20.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_066401
Uniprot Accession Number
P01567
Species
Human
N Terminal Sequence
Ala
AA Sequence
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