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Recombinant human IFN-alpha 7/IFNA7 protein

IFNA7, also known as interferon alpha-7, is a member of the interferon family. Interferon promotes the production of two enzymes, protein kinase and oligoadenylate synthetase. They allow the cells to communicate with the protective barrier of the immune system to eradicate pathogens or tumors. IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. IFN-alpha has both anti-viral and immunomodulatory activities on target cells, and increases the awareness of infection or tumor cells by elevating antigen presentation to T lymphocytes. This protein has both anti-viral and immunomodulatory activities on target cells and involved both in ligand binding and signal transduction. Recombinant human IFNA7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interferon alpha-7, IFNA7, IFN-alphaJ, IFNA-J, Interferon alpha-J1, IFN-alpha-J1

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

20.7 kDa (175aa)

Additionnal Information

IFNA7, Interferon alpha-7, IFNA7, IFN-alphaJ, IFNA-J, ATGP3810-10 µg, ATGP3810-20 µg, ATGP3810-50 µg, ATGP3810-100 µg, ATGP3810-250 µg, ATGP3810-500 µg, ATGP3810-1 mg, ATGP3810-10, ATGP3810-20, ATGP3810-50, ATGP3810-100, ATGP3810-250, ATGP3810-500, ATGP3810-1

References & Citations

De Veer MJ., et al. (2001) J Leukoc Biol. 69:912-920.; ; Fensterl V., et al. (2009) Biofactors. 35:14-20.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_066401

Uniprot Accession Number

P01567

Species

Human

N Terminal Sequence

Ala

AA Sequence

CDLPQTH SLRNRRALIL LAQMGRISPF SCLKDRHEFR FPEEEFDGHQ FQKTQAISVL HEMIQQTFNL FSTEDSSAAW EQSLLEKFST ELYQQLNDLE ACVIQEVGVE ETPLMNEDFI LAVRKYFQRI TLYLMEKKYS PCAWEVVRAE IMRSFSFSTN LKKGLRRKD
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