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Recombinant human BMP-2 protein

BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factor that belongs to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility. Recombinant human BMP2 was expressed in E. coli and purified by conventional chromatography techniques.

Product Specifications

Product Name Alternative

Bone morphogenetic protein 2, BMP-2A

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

13.0 kDa (115aa)

Additionnal Information

BMP2, Bone morphogenetic protein 2, BMP-2A, ATGP3787-10 µg, ATGP3787-20 µg, ATGP3787-50 µg, ATGP3787-100 µg, ATGP3787-250 µg, ATGP3787-500 µg, ATGP3787-1 mg, ATGP3787-10, ATGP3787-20, ATGP3787-50, ATGP3787-100, ATGP3787-250, ATGP3787-500, ATGP3787-1

References & Citations

Chen D., et al. (2004) . Growth factors. 22 (4) :233-41; ; Schliephake H., et al. (2005) . Clin Oral Implants Res. 17 (6) :666-72

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 10 mM Sodium acetate (pH 3.5)

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_001191

Uniprot Accession Number

P12643

Species

Human

AA Sequence

MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

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