Recombinant human EPXH1 protein
EPHX1, also known as epoxide hydrolase 1, is an important bioconversion enzyme that converts epoxides from degradation of aromatics into trans-dihydrodiols that can be conjugated and excreted in the body. The epoxide hydrolase acts both in the activation and decryption of the epoxide. This enzyme plays a role in regulating the extensive oxidation state of heterologous and lipid-derived substrates. Mutations in this gene cause preeclampsia, lack of epoxidase, or increased epoxide hydrolase activity. Recombinant human EPHX1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Epoxide hydrolase 1, EPHX1, EPHX, EPOX, HYL1, MEH
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 85% by SDS-PAGE
Molecular Weight
51.5 kDa (442aa)
Additionnal Information
References & Citations
Hartsfield JK Jr., et al. (1988) Cytogenet Cell Genet. 83:44-45.; ; Neurosci Bull., et al. (2016) Epub. 32:545-546
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 1mM DTT, 0.1M NaCl
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_000111
Uniprot Accession Number
P07099
Species
Human
N Terminal Sequence
Met
Frequently Asked Questions
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