Recombinant mouse Biliverdin Reductase B/BLVRB protein
Blvrb, also known as flavin reductase (NADPH) isoform 1, is an enzyme (EC 1. 3. 1. 24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. Blvrb is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant mouse Blvrb protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Flavin reductase, NADPH, Biliverdin reductase B, BVR-B, Biliverdin-IX beta-reductase, NADPH-dependent diaphorase, NADPH-flavin reductase, FLR, FR
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Purity
> 95% by SDS-PAGE
Molecular Weight
24.6 kDa (229aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Baranano DE., et al. (2002) . Proc Natl Acad Sci USA. 99 (25) :16093-8.; ; Saito F., et al. (1995) Cytogenet Cell Genet. 71 (2) :179-81.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Redox Proteins
NCBI Accession Number
NP_659172
Uniprot Accession Number
Q923D2
Species
Mouse
AA Sequence
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