Recombinant human CD3 zeta/CD247 protein

CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.2 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

14.1 kDa (122aa)

Additionnal Information

TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247, ATGP3754-10 µg, ATGP3754-20 µg, ATGP3754-50 µg, ATGP3754-100 µg, ATGP3754-250 µg, ATGP3754-500 µg, ATGP3754-1 mg, ATGP3754-010, ATGP3754-020, ATGP3754-050, ATGP3754-100, ATGP3754-250, ATGP3754-500, ATGP3754-01M