Recombinant human SP-D protein

SFTPD, also known as pulmonary surfactant-associated protein D, is a member of the collectin family of innate immune modulators. It contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. This protein interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. Recombinant human SFTPD protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Pulmonary surfactant-associated protein D, SFTPD, COLEC7, PSP-D, SFTP4, SP-D

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

36.5 kDa (363aa)

Additionnal Information

SP-D, Pulmonary surfactant-associated protein D, SFTPD, COLEC7, PSP-D, SFTP4, SP-D, ATGP3747-10 µg, ATGP3747-20 µg, ATGP3747-50 µg, ATGP3747-100 µg, ATGP3747-250 µg, ATGP3747-500 µg, ATGP3747-1 mg, ATGP3747-10, ATGP3747-20, ATGP3747-50, ATGP3747-100, ATGP3747-250, ATGP3747-500, ATGP3747-1

References & Citations

Soto-Cardenas MJ., et al, (2015) J Rheumatol. 42:111-118.; ; Sorensen GL., et al, (2016) Atherosclerosis. 246:7-12.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Ubiquitination

NCBI Accession Number

NP_003010

Uniprot Accession Number

P35247

Species

Human

N Terminal Sequence

Ala

AA Sequence

EMKTYSH RTMPSACTLV MCSSVESGLP GRDGRDGREG PRGEKGDPGL PGAAGQAGMP GQAGPVGPKG DNGSVGEPGP KGDTGPSGPP GPPGVPGPAG REGPLGKQGN IGPQGKPGPK GEAGPKGEVG APGMQGSAGA RGLAGPKGER GVPGERGVPG NTGAAGSAGA MGPQGSPGAR GPPGLKGDKG IPGDKGAKGE SGLPDVASLR QQVEALQGQV QHLQAAFSQY KKVELFPNGQ SVGEKIFKTA GFVKPFTEAQ LLCTQAGGQL ASPRSAAENA ALQQLVVAKN EAAFLSMTDS KTEGKFTYPT GESLVYSNWA PGEPNDDGGS EDCVEIFTNG KWNDRACGEK RLVVCEF