Recombinant human SP-D protein
SFTPD, also known as pulmonary surfactant-associated protein D, is a member of the collectin family of innate immune modulators. It contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. This protein interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. Recombinant human SFTPD protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Pulmonary surfactant-associated protein D, SFTPD, COLEC7, PSP-D, SFTP4, SP-D
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
36.5 kDa (363aa)
Additionnal Information
References & Citations
Soto-Cardenas MJ., et al, (2015) J Rheumatol. 42:111-118.; ; Sorensen GL., et al, (2016) Atherosclerosis. 246:7-12.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Ubiquitination
NCBI Accession Number
NP_003010
Uniprot Accession Number
P35247
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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