Recombinant human DAP10/HCST protein

HCST, also known as hematopoietic cell signal transducer isoform 1, is a member of the DAP10 family. It can be part of an immunoreceptor complex. This receptor plays an important role in inducing cytotoxicity against MHC class I chain-associated MICA and target cells expressing cell surface ligands such as MICB and UL16-binding protein (ULBP) . This receptor complex can play a role in cell survival and proliferation by activation of NK and T cell responses. Recombinant human HCST, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Hematopoietic cell signal transducer isoform 1, HCST, DAP10, KAP10, PIK3AP

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

30.1 kDa (271aa)

Additionnal Information

DAP10, HCST, Hematopoietic cell signal transducer isoform 1, HCST, DAP10, KAP10, PIK3AP, ATGP3745-10 µg, ATGP3745-20 µg, ATGP3745-50 µg, ATGP3745-100 µg, ATGP3745-250 µg, ATGP3745-500 µg, ATGP3745-1 mg, ATGP3745-10, ATGP3745-20, ATGP3745-50, ATGP3745-100, ATGP3745-250, ATGP3745-500, ATGP3745-1