Recombinant human ASAM protein

CLMP, also known as CXADR like membrane protein, is a type 1 transmembrane protein and member of the CTX family within the immunoglobulin superfamily. This protein is highly expressed in the small intestine and placenta, and is found at intermediate levels in the heart, skeletal muscle, colon, and lung and appears in low levels in the liver and peripheral blood leukocytes as well. It is localized to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion. Also, it plays a role in adipocyte differentiation and development of obesity. Recombinant human CLMP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CXADR like membrane protein, CLMP, ACAM, ASAM, CSBM, CSBS

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

25.6 kDa (226aa)

Additionnal Information

ASAM, CXADR like membrane protein, CLMP, ACAM, ASAM, CSBM, CSBS, ATGP3742-10 µg, ATGP3742-20 µg, ATGP3742-50 µg, ATGP3742-100 µg, ATGP3742-250 µg, ATGP3742-500 µg, ATGP3742-1 mg, ATGP3742-10, ATGP3742-20, ATGP3742-50, ATGP3742-100, ATGP3742-250, ATGP3742-500, ATGP3742-1

References & Citations

Eguchi J., et al, (2005) Biochem J. 387:343-353.; ; Sze KL., et al, (2006) J Cell Physiol. 214:334-344.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 1mM DTT, 20%glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_079045

Uniprot Accession Number

Q9H6B4

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPTHTEIKR VAEEKVTLPC HHQLGLPEKD TLDIEWLLTD NEGNQKVVIT YSSRHVYNNL TEEQKGRVAF ASNFLAGDAS LQIEPLKPSD EGRYTCKVKN SGRYVWSHVI LKVLVRPSKP KCELEGELTE GSDLTLQCES SSGTEPIVYY WQRIREKEGE DERLPPKSRI DYNHPGRVLL QNLTMSYSGL YQCTAGNEAG KESCVVRVTV QYVQSIGMVA HHHHHH