Recombinant human CD164 protein
CD164, also known as sialomucin core protein 24 isoform 1, is a type I transmembrane O-glycosylated protein that is expressed on activated perivascular and stromal cells in embryonic and tumor neovasculature. It plays a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38 (lo/-) cell proliferation. This protein also plays an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Recombinant human CD164 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Sialomucin core protein 24 isoform 1, CD164, DFNA66, endolyn, MGC-24, MGC-24v, MUC-24
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 85% by SDS-PAGE
Molecular Weight
15.6 kDa (148aa)
Additionnal Information
References & Citations
Huang AF., et al, (2013) Mol Cancer. 12:115.; ; Guenova E., et al, (2016) Acta Derm Venereol. 96:464-467.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_006007
Uniprot Accession Number
Q04900
Species
Human
N Terminal Sequence
Ala
AA Sequence
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