Recombinant human SLP-76/LCP2 protein
LCP2, also known as lymphocyte cytosolic protein 2, is an intracellular docking protein with a single SH2 recognition domain. It is involved in T-cell antigen receptor mediated signaling. This protein is phosphorylated by ZAP70 leading to NF-AT and IL2 gene activation. Recombinant human LCP2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Lymphocyte cytosolic protein 2, LCP2, SLP-76, SLP76
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
61.2 kDa (542aa)
Additionnal Information
References & Citations
Siggs OM., et al, (2015) J Immunol. 194:2587-2595.; ; Danzer C., et al, (2016) Eur J Immunol. 46:2121-2136.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_005556
Uniprot Accession Number
Q13094
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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