Recombinant human IL-7R alpha/IL7R protein
IL7R, also known as interleukin-7 receptor, is a hematopoietin receptor superfamily member. It plays important role in lymphocyte differentiation, proliferation, multiple sclerosis, and survival. This protein signaling is essential for T-cell development and regulation of native and memory T-cell homeostasis. Also, it is critically required for the proper development and function of lymphoid cells. Recombinant human IL7R, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interleukin 7 receptor, Interleukin-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127, CDw127, lnc-IL7R
Expression System
Baculovirus
Antigen Species
Human
Tag
HIgG-His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
52.5 kDa (461aa)
Additionnal Information
References & Citations
Goodwin RG., et al, (1990) Cell 60:941-951.; ; Melao A., et al, (2016) Haematologica 101:1368-1379.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_002176
Uniprot Accession Number
P16871
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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