Recombinant human CD163 protein
CD163, also known as scavenger receptor cysteine-rich type 1 protein M130 isoform a, is a scavenger receptor for the hemoglobin-haptoglobin complex that is essential in liver, spleen and circulation. This protein is generated by ectodomain shedding of the membrane bound receptor. Also, it is upregulated in a large range of inflammatory diseases including liver cirrhosis, macrophage activation syndrome, HIV infection and sepsis. Recombinant human CD163, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Scavenger receptor cysteine-rich type 1 protein M130 isoform, CD163, M130, MM130, SCARI1
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
109.8 kDa (1015aa)
Additionnal Information
References & Citations
Droste A., et al, (1999) Biochem. Biophys. Res. Commun. 256:110-113.; ; Stover CM., et al, (2000) Cytogenet. Cell Genet. 90:246-247.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Scientific Category
Immunology
NCBI Accession Number
NP_004235
Uniprot Accession Number
Q86VB7
Species
Human
N Terminal Sequence
Ser42
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