Recombinant human CD107a/LAMP1 protein

LAMP1, also known as lysosome-associated membrane glycoprotein 1, is a membrane protein that belongs to the LAMP family. It is expressed in the endosome-lysosome membranes of cells, but is also found on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP1 is expressed on the surface of activated macrophages where it promotes T cell co-stimulation and a Th1 biased immune response. Recombinant human LAMP1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Lysosome-associated membrane glycoprotein 1, LAMP1, CD107a, LAMPA, LGP120, CD107 antigen-like family member A

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

39.4 kDa (363aa)

Additionnal Information

LAMP1, CD107a, Lysosome-associated membrane glycoprotein 1, LAMP1, CD107a, LAMPA, LGP120, ATGP3694-10 µg, ATGP3694-20 µg, ATGP3694-50 µg, ATGP3694-100 µg, ATGP3694-250 µg, ATGP3694-500 µg, ATGP3694-1 mg, ATGP3694-10, ATGP3694-20, ATGP3694-50, ATGP3694-100, ATGP3694-250, ATGP3694-500, ATGP3694-1

References & Citations

Dange MC., et al, (2015) Mol Cell Biochem. 404:79-86.; ; Okato A., et al, (2016) Int J Oncol. 49:111-122.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_005552

Uniprot Accession Number

P11279

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPAMFMVKN GNGTACIMAN FSAAFSVNYD TKSGPKNMTF DLPSDATVVL NRSSCGKENT SDPSLVIAFG RGHTLTLNFT RNATRYSVQL MSFVYNLSDT HLFPNASSKE IKTVESITDI RADIDKKYRC VSGTQVHMNN VTVTLHDATI QAYLSNSSFS RGETRCEQDR PSPTTAPPAP PSPSPSPVPK SPSVDKYNVS GTNGTCLLAS MGLQLNLTYE RKDNTTVTRL LNINPNKTSA SGSCGAHLVT LELHSEGTTV LLFQFGMNAS SSRFFLQGIQ LNTILPDARD PAFKAANGSL RALQATVGNS YKCNAEEHVR VTKAFSVNIF KVWVQAFKVE GGQFGSVEEC LLDENSMHHH HHH