Recombinant human CD107a/LAMP1 protein
LAMP1, also known as lysosome-associated membrane glycoprotein 1, is a membrane protein that belongs to the LAMP family. It is expressed in the endosome-lysosome membranes of cells, but is also found on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP1 is expressed on the surface of activated macrophages where it promotes T cell co-stimulation and a Th1 biased immune response. Recombinant human LAMP1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Lysosome-associated membrane glycoprotein 1, LAMP1, CD107a, LAMPA, LGP120, CD107 antigen-like family member A
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
39.4 kDa (363aa)
Additionnal Information
References & Citations
Dange MC., et al, (2015) Mol Cell Biochem. 404:79-86.; ; Okato A., et al, (2016) Int J Oncol. 49:111-122.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_005552
Uniprot Accession Number
P11279
Species
Human
N Terminal Sequence
Ala
AA Sequence
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