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Recombinant human CDK5 protein

CDK5, also known as cyclin-dependent-like kinase 5 isoform 1, is a member of the cyclin dependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. This is activated by association with a neuron-specific activator, p35 or its isoform p39. CDK5 is probably involved in the control of the cell cycle. Recombinant human CDK5 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Cyclin-dependent-like kinase 5 isoform 1, CDK5, LIS7, PSSALRE

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

34.1 kDa (298aa)

Additionnal Information

CDK5, Cyclin-dependent-like kinase 5 isoform 1, CDK5, LIS7, PSSALRE, ATGP3683-10 µg, ATGP3683-20 µg, ATGP3683-50 µg, ATGP3683-100 µg, ATGP3683-250 µg, ATGP3683-500 µg, ATGP3683-1 mg, ATGP3683-10, ATGP3683-20, ATGP3683-50, ATGP3683-100, ATGP3683-250, ATGP3683-500, ATGP3683-1

References & Citations

Shupp A., et al, (2017) Oncotarget. 8:17373-17382.; ; Na YR., et al, (2015) Sci Signal. 8:ra121.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 40% glycerol, 1mM DTT

Scientific Category

Cell Cycle

NCBI Accession Number

NP_004926

Uniprot Accession Number

Q00535

Species

Human

N Terminal Sequence

Met1

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